Approved Grant Summary 2007 – 2024

2024

Researcher: Audrey Milburn
Topic: Characterisation of HDAC4 aggregates

Researcher: Toby Fuller
Topic: Assessing fatigue in Adult Blood Cancer patients

Researcher: Helen Fitzsimons
Topic: Investigating the regulation of HDAC4 in ageing and neurodegenerative disease

Researcher: Kathryn Stowell
Topic: Investigating RYR1 variants

Researcher: Ajit Purba
Topic: Intestinal enterocyte and M-cell co-culture cell model validation

Researcher: Jasna Rakonjac
Topic: Genetic basis of horizontal antibiotic resistance spread; targeting a bacteria-bacteriophage partnership

Researcher: Suzanne Hodgkinson
Topic: Anabolic resistance in ageing and the role of the limiting indispensable amino acid in determing the protein synthesis and breakdown response to meal protein quality

Researcher: Tracy Hale
Topic: The role of HPIα in Telomeric Heterochromatin

Researcher: Balakrishnan Nair
Topic: Feasbility study on digital technologies for stroke and CVD prevention

2023

Researcher: Noha Nasef
Topic: Benefits of consuming apples for patients with ulcerative colitis.

Researcher: Tracy Hale
Topic: HPIα represses cancer related gene promoters

Researcher: Martin Allen
Topic: Novel Microfluidic Chip Fabrication Method for Parasite Analysis

Researcher: Christina Severinsen
Topic: Waihi Korero: Challenging unmet need

Researcher: Maria Gomez-Lozano
Topic: Reducing cholesterol using bioparticles displaying enzymes from probiotic bacteria

2021

Researcher: Dr Juan C. Gacia-R
Topic: Geonomic Signatures of New Cryptosporidium infecting Humans.

Researcher: Mr Muhammad Rehan
Topic: Pill Sized Robotic Capsule to Collect Gut Microbiota and Digesta

Researcher: Dr Louise Brough
Topic: Iodine & Selenium in Relation to Thyroid Function in Women with Coeliac Disease

Researcher: Dr Evelyn Sattelgger
Topic: Towards the Characterisaiton of IMAPCT

Researcher: Dr Helen Fitzsimons
Topic: Does HDAC4 Intron Retention Promote Neuronal Degeneration?

Researcher: Dr Tracy Hale
Topic: Identifying the Role of G4 Assemblies Play in Regulating Oncogene Expression.

2020

Researcher: Mr Victor Barnes
Topic: Inside the parasite egg: A Microrobotics approach to analyse cryptosporidium

Researcher: Miss Holly Gray
Topic: Geonomic Epidemiolgy of ESBLs

Researcher: Dr Lynette Hodges
Topic: Transforming Lives: One step at a time

Researcher: Dr Louise Brough
Topic: Determination of selenium and zinc in pregnancy

Researcher: Miss Ella Rose Eagar
Topic: Characterization of variants associated with Malignant Hyperthermia

Researcher: Dr Laryssa Howe
Topic: HPV types present in cervical biopsies with histologically confirmed high grade dysplasia, and a negative cobas high risk HPV test result

Researcher: Dr Clarie Hardie
Topic: Engagement with Maori whanau on CT screening for lung cancer in Maori

2019

Researcher: Lucy Rowe
Topic: The Koru Study – Body composition changed during Pregnancy and Early Infancy

Researcher: Hannah Hawley
Topic: Focus on the foci – Investigating the role of HDAC4 aggregation on neuronal function

Researcher: Dr Caroline Giezenaar
Topic: Effects of milk proteins on brain serotonin

Researcher: Katie Schraders
Topic: Close to the Bone – an investigation of bone health in young women with Coeliac Disease

Researcher: Dr Jasna Rakonjac
Topic: Rapid detection assay for bacterial toxins

Researcher: Professor Kathryn Stowell
Topic: Genetic Diagnosis of Malignant Hyperthermia

2018

Researcher: Dr Sara Burgess
Topic: Plasmid mediated antimicrobial resistance/ Dissemination of ARM in waterways

Researcher: Dr Ryan Chanyi
Topic: Bacterial adaptation to low-dose antibiotics: Evolutionary Phenomics

Researcher: Dr Jane Coad
Topic: The gut-bone axis in Coeliac Disease

Researcher: Dr Tracy Hale
Topic: Modelling heterochromatin organisation

Researcher: Dr Hayley Hunt
Topic: Investigation of an unexplained myopathy in dogs: causative compounds in wild pork

Researcher: Dr Matthew Savoian
Topic: Centrosomes control cell division for sperm formation

Researcher: Dr Jasmine Thomson
Topic: Footprint Study

Researcher: Dr Jeong Park
Topic: Inhibitors of immune evasion in brain cancer

2017

Researcher: Miss Remai Parker – Year 3
Topic: Calcium dysregulation in skeletal muscle (Duncan
Scholarship = $25k per yr for 3 yrs plus $10k consumables per year for 3 yrs)

Researcher: Dr Darryl Cochrane
Topic: The acute affect of vibration for people with peripheral arterial disease

Researcher: Dr Lynette Hodges
Topic: Well ME

Researcher: Dr Marlena Kruger
Topic: The association between dietary patterns, the gut microbiome and bone health in postmenopaulsal women living in the Manawatu

Researcher: Dr Shahista Nisa
Topic: A novel strain of Leptospira: Taxonomy, Serology & Epidemiology

Researcher: Dr Anja Schiemann
Topic: Functional characterisation of RYR1 variants using immortalised myoblasts

Researcher: Dr Elena Harjes
Topic: Using nucleic acid-based inhibitors of APOBEC3 enzymes to reduce mutational load in cancers

Researcher: Dr Joanna Roberts
Topic: Essential cell division protein Ki67-measuring its enduring qualities for better diagnostic testing

Researcher: Mr Harry Cookson
Topic: Multi-drug resistant Enterobacteriaceae

2016

Researcher: Miss Remai Parker – Year 2
Topic:  Calcium dysregulation in skeletal muscle (Duncan
Scholarship = $25k per yr for 3 yrs plus $10k consumables per year for 3 yrs)

Researcher: Mr Samuel Bloonfield
Topic:  Factors influending long-term Camphlobacter excretion

Researcher: Dr Sara Burgess
Topic:  Prevalence of multidrug resistant Enterobacteriaceae in livestock

Researcher: Miss Maggie Chan
Topic:  Cryptosporidium infection assay development

Researcher: Dr Helen Fitzsimons
Topic:  Modelling CoenzymeQ deficiency in Drosophilia

Researcher: Dr Robert Jolly
Topic:  Gene therapy in a canine model of mucopolysaccharidosis Illa

Researcher: Dr Anne Midwinter
Topic:  Tracing the cryptic source of human yersiniosis viamolecular epidemiology

Researcher: Dr Max McCann
Topic:  To enable Prof. Hesketh to come out from the UK to speak on Low Selenium Intake as a Risk Factor

Researcher: Ms Hannah Morton
Topic:  The incidence of inflammatory bowel disease in Manawatu

Researcher: Dr Shahista Nisa
Topic:  Pathogenesis of Shiga toxin-producing E.coli isolated from farms in New Zealand

Researcher: Dr Tracy Hale
Topic:  Targeting the nuclear periphery to halt malignancy

2015

Researcher: Miss Remai Parker – Year 1
Topic:  Calcium dysregulation in skeletal muscle (Duncan
Scholarship = $25k per yr for 3 yrs plus $10k consumables per year for 3 yrs)

Researcher: Dr Adrian Cookson
Topic:  Genomic Epidemiology of STEC0145

Researcher: Dr Kene Dittmer
Topic:  Changes in skeletal gene expression in a sheep model of osteoporosis

Researcher: Mr James Hansen
Topic:  Female reproductive organoid combination to progress regenerative medicine

Researcher: Mrs Haley Hunt
Topic:  Investigation of an unexplained myopathy in dogs

Researcher: Dr Jasna Rakonjac
Topic:  Novel synergies for combat against Gram-negative bacteria

Researcher: Dr Anja Schiemann
Topic:  Exploring RyR1 channel function in an inducible system

Researcher: Dr Rutvik Vanamala
Topic:  In vitro susceptibility of Propionibacterium acnes to surgical preparation agents

Researcher: Dr Laryssa Howe
Topic:  Human Papillomavirus (HPV) associated oropharyngeal
squamous cell carcinoma

Researcher: Dr Geoff Kira
Topic:  Simple strategies for improving cardiac rehabilitation uptake and attendance

Researcher: Ms Tessa Nielson
Topic:  Physiological and gene responses in CFS patients

Researcher: Mr Liam McRedmond
Topic:  Follow up on malignant hyperthermia patients tested MHS (susceptible) to either caffeine or halothane

2014

Researcher: Miss Remai Parker
Topic:  Calcium dysregulation in skeletal muscle (Duncan
Scholarship = $25k per yr for 3 yrs plus $10k consumables per year for 3 yrs)

Researcher: Dr Jane Coad
Topic:  Paneth cells in inflammatory bowel disease

Researcher: Dr Helen Fitzsimons
Topic:  Investigating the role of moesin in memory formation

Researcher: Dr Tracey Hale
Topic:  TERRA in Telomere function

Researcher: Dr Jeong Park
Topic:  Novel Molecular mechanisms underlying neurodegenerative diseases

Researcher: Dr Raewyn Poulsen
Topic:  Producing Lenti-vectors to over-express and knockdown bmal1 in primary chondrocytes

Researcher: Dr Jasna Rakonjac
Topic:  Secretin stress in Escherichia coli

Researcher: Dr Jeong Park
Topic:  Therapeutic intervention of a novel enzyme target for cancer therapy

Researcher: Miss Amy Lynch
Topic:  Does a live probiotic improve GI motility in in vitro models?

Researcher: Mr Sean Massey
Topic:  Candidate genes for malignant hyperthermia

Researcher: Miss Rebecca Wong
Topic:  HLAB27 patient syrvey

2013

Researcher: Dr Mary Breheny
Topic:  Developing the health work and retirement study as a lifetime longitudinal study

Researcher: Dr Christopher Kendrick
Topic:  Cell free fetal DNA genotyping to predict fetal Rh(d) groups during pregnancy

Researcher: Dr Mary Nulsen
Topic:  emm-type distribution in throat isolates of Group A streptococci

Researcher: Dr Jasna Rakonjac
Topic:  Interactions of probiotic Lactobacillus Rhamnosus with gut intestinal cells

Researcher: Dr Wendi Roe
Topic:  Hypermucoviscous Klebsiella Pneumoniae in NZ

Researcher: Dr Matthew Savoian
Topic:  Meiotic kinetochore composition and function

Researcher: Dr Anja Schiemann
Topic:  Functional analysis of MH associated mutations

Researcher: Dr Tracy Hale
Topic:  Does HP1a suppress invasion

Researcher: Dr Vyacheslav Filichev
Topic:  G4 – specific helicase inhibitors assay

Researcher: Ms Jenny Wong
Topic:  Rates and treatment cost of tumour recurrence in a provincial NZ oncology centre

Researcher: Ms Chin Chuevin
Topic:  Identification of MSK1 mutants for tumour suppression

2012

Researcher: Dr Els Acke
Topic:  Campylobacter spp.Gastro-enteritis disagnosis in NZ (Returned $7051.07 unspent)

Researcher: Dr Keren Dittmer
Topic:  Genetic diseases in NZ livestock as models for human disease

Researcher: Dr Helen Fitzsimons
Topic:  MEF2: a checkpoint for memory formation

Researcher: Dr Kathryn Stowell
Topic:  Engineering RYR1 to explore channel function

Researcher: Dr Wei-Hang Chua
Topic:  The effect of omega-3 fatty acids on osteocyte-mediated mechanotransduction

Researcher: Dr Tracy Hale
Topic:  Does aberrant hostone H1 phosphorylation contribute to cellular transformation

Researcher: Dr Mark McCann
Topic:  Tumour suppression in cancer: more than just loss of function

Researcher: Dr Anna Ranta
Topic:  Feasibility of an International Tele-Stroke Service FITS

Researcher: Ms Yasmin Dijkwel
Topic:  In the Heterochromatin Protein 1 family involved in tumour invasion

Researcher: Ms Elizabeth Thomas
Topic:  Pre-operative management of anaemia to minimise
perioperative transfusion requirements and morbidity

2011

Researcher: Dr Jonathan Bray
Topic:  Can Thalidomide Improve Survival in Canine

Researcher: Ms Sarah Buchanan
Topic:  Vitamin D and risk of metabolic syndrome

Researcher: Dr Tracy Hale
Topic:  Heterochromatin Protein 1: A roadblock for invasion

Researcher: Ms Clare Hollewand
Topic:  Structure-function analysis of Nuclear Receptors inp21 cell cycle inhibitor-targeted cancer therapy

Researcher: Dr Adrian Jules Marquet
Topic:  Vibration training to reduce the loss of bone mineraldensity after spinal cord injury (Funds Returned as project stopped)

Researcher: Dr Mark McCann
Topic:  Proteomic and metabolomic regulation of prostate cancer progression

Researcher: Mr Aus Molan
Topic:  Methicillin-resistant Staphylococcus aureus (MRSA)isolation from nasal and throat swabs; detection by real time PCR and culture

Researcher: Dr Jeong Park
Topic:  Anti-aging effects of brain cancer-Amplified Gene GAS41

Researcher: Dr Jasna Rakonjac
Topic:  Envelope stress in Escherichia coli

Researcher: Mr Preet Singh
Topic:  Pharmacology of choline

Researcher: Ms Aimee Renee Woods
Topic:  FLNA Project

2010

Researcher: Dr Andrew Sutherland-Smith
Topic:  Defining the Ruthenium Antitumor Drug Binding Site on Human Serum Albumin (Refund $117.30 rcv’d1/8/2012)

Researcher: Ms Danielle Aberdein
Topic:  A lymphoproliferative disease in Manx cats with similarities to autoimmune lymphoproliferative syndrome (ALPS) in people (Refund $1090.22 rcv’d 20/3/2013)

Researcher: Dr Els Acke
Topic:  ProSpecT ELISA Camphylobacter spp. detection (Refund rcv’d $252.55 13/11/2012)

Researcher: Dr Emma Bermingham
Topic:  Felis Catus: A novel model for investigating the food-microbehost interactin during obesity

Researcher: Dr Louise Brough
Topic:  Iodine & Selecium intake of pregnant and lactating women in Manawatu

Researcher: Dr Keren Dittmer
Topic:  Drug-induced read through of the premature stop codon in corridale sheep

Researcher: Dr Laryssa Howe
Topic:  Prevalence of Toxoplasma in meat

Researcher: Dr Christopher Jones
Topic:  Preparation of anaesthetic machines for malignant hyperthermia susceptible patients

Researcher: Dr Jasna Rakonjac
Topic:  Sensitising Klebsiella to antibiotics

Researcher: Dr Mark McCann
Topic:  MidCentral Electronic Decision Support Stroke Prevention Study

Researcher: Dr Anna Ranta
Topic:  MidCentral Electronic Decision Support Stroke Prevention Study

Researcher: Dr Kathryn Stowell
Topic:  Differential gene expression in chemotherapy for colon cancer

Researcher: Ms Courtney Meredith
Topic:  Anti-Cancer effects of Eleic Acid in the regulation of p53 tumour suppressor

2009

Researcher: Prof. Robert Jolly
Topic:  The effect of Postural Changes on Intrathecal Enzyme Replace Therapy in Lysosomal Storage Diseases

Researcher: Dr Andrew Sutherland-Smith
Topic:  Defining the Ruthenium Antitumor Drug Binding Site on Human Serum Albumin

Researcher: Dr Clare Randall
Topic:  Intransal Midazolam for the Palliation of Dyspnoea in Patients with Life-Limiting Disease

Researcher: Dr Kathryn Stowell
Topic:  Transcriptome Analysis in Colon Cancer

Researcher: Matilda Newton
Topic:  Untangling Topoisomerase Iia Expression

Researcher: Rebecca Smith
Topic:  Site-directed Mutational Analysis of p53 Tumour Suppressor in Cterminal Endoproteolysis

2008

Researcher: Dr Nick Cave
Topic:  Neuroinflammation in Mucopolysaccharidosis IIIa

Researcher: Dr Alastair Johnstone
Topic:  The Primary Cilium in Ovine Polycystic Kidney Disease

Researcher: Dr Jasna Rakonjac
Topic:  The Role of a Cellbinding Protein in Probiotic Traits of Lactobacillus Rhamnosus HN001

2007

Researcher: Ms Keren Dittmer
Topic:  Inherited Rickets in Corredale Sheep

Researcher: Assoc Prof Max Scott
Topic:  The Molecular Basis of Maggot Therapy

Researcher: Dr Stephen Stannard
Topic:  Effect of Vibration Training on Functional Strength of MS Patients

Researcher: Dr Jasna Rakonjac
Topic:  Develooping Bi-Functional Nanoparticles For Diagnostics

Researcher: Dr Robert Ronimus
Topic:  The Role of a Novel Mammauan ASP-Dependent Glucoknase in the Energy Metaboism of the Heart

Researcher: Ms Kate Silverwood
Topic:  Drug Sensitivity in Melanoma